3-Hydroxy-3-[(2-methylpropanoyl)methyl]indolin-2-one
نویسندگان
چکیده
The title compound, C(13)H(15)NO(3), was synthesized by the Aldol reaction of isatin and 3-methyl-butan-2-one refluxing in methanol catalyzed by dimethyl-amine. The packing of the mol-ecules in the crystal structure features inter-molecular N-H⋯O and O-H⋯O hydrogen bonds.
منابع مشابه
3-Hydroxy-3-nitromethylindolin-2-one
In the title compound, C(9)H(8)N(2)O(4), the indolin-2-one ring system is substanti-ally planar [maximum deviation = 0.0353 (15) Å]. In the crystal structure, inter-molecular N-H⋯O and O-H⋯O hydrogen bonds are responsible for the formation of a three-dimensional network.
متن کامل6-Hydroxy-3-(hydroxyimino)indolin-2-one
In the title compound, C(8)H(6)N(2)O(3), the indol-2-one system is almost planar [maximum deviation = 0.010 (3) Å]. In the crystal structure, inter-molecular N-H⋯O, O-H⋯N and O-H⋯O hydrogen bonds link the mol-ecules into a three-dimensional network. π-π contacts between the indole ring systems [centroid-centroid distances = 3.494 (1), 3.731 (1) and 3.736 (1) Å] may further stabilize the structure.
متن کاملCatalyst and Solvent-Free Microwave Assisted Expeditious Synthesis of 3-Indolyl-3-hydroxy Oxindoles and Unsymmetrical 3,3-Di(indolyl)indolin-2-ones
A simple and efficient method for the synthesis of 3-indolyl-3-hydroxy oxindoles and unsymmetrical 3,3-di(indolyl)indolin-2-ones using microwave irradiation without catalyst and solvent is described. A series of 3-indolyl-3-hydroxy oxindoles and unsymmetrical 3,3-di(indolyl)indolin-2ones have been synthesized in very short reaction times of 5 and 10 minutes and in yields ranging from 31% to 98%...
متن کامل1-[(Diethylaminocarbonyl)methyl]-2-[hydroxy(6-methoxyquinolin-4-yl)methyl]-5-vinyl-1-azoniabicyclo[2.2.2]octane chloride monohydrate
In the title compound, C(26)H(36)N(3)O(3) (+)·Cl(-)·H(2)O, the mol-ecular structure of the cation is stabilized by a number of C-H⋯O intra-molecular inter-actions. In the crystal structure, O-H⋯Cl and C-H⋯Cl hydrogen bonds link the ions into a ribbon-like structure along the a axis.
متن کاملN-[(2-Hydroxy-5-methoxyphenyl)(3-nitrophenyl)methyl]acetamide
In the title compound, C(16)H(16)N(2)O(5), the meth-oxy group is disordered with site occupancies of 0.20 (3) and 0.80 (3). The dihedral angle between the two aromatic rings is 73.7 (2)°. The crystal structure is characterized by intermolecular N-H⋯O, O-H⋯O, C-H⋯O and C-H⋯π hydrogen bonds.
متن کامل